Katie Houghton, MSc

Director, Synthesis and Statistics

MSc, Social Research Methods and Statistics
The University of Manchester, Manchester, United Kingdom

BSc, Psychology: Physical and Mental Health
University of Reading, Berkshire, United Kingdom

Katherine Houghton, MSc, is a Director in the Health Economics Database group at RTI-HS. Ms. Houghton has extensive experience in health outcomes research and data analytics, including experience in manipulating, cleaning, and conducting analyses of clinical trial and observational data using both Stata and Mplus. Ms. Houghton’s primary responsibilities are designing and implementing observational studies (such as medical record reviews and surveys) and retrospective data analysis. Specifically, Ms. Houghton has expertise in conducting advanced statistical analyses, including structural equation modeling and analysis of heterogeneity to identify empirically-derived subgroups. Ms. Houghton’s key area of expertise is the explicit consideration of missing data (including analytic techniques for missing data mechanisms that are nonignorable) and implications on results. She has experience in applying structural equation modeling techniques (including latent growth modeling and growth mixture modeling) under different assumptions around missing data, such as multiple imputation, full information maximum likelihood, and pattern-mixture modeling. She also uses latent growth modeling and growth mixture modeling to examine the heterogeneity of responses in clinical trials and observational studies. Ms. Houghton’s therapeutic areas of interest include invasive fungal infections, neurology, oncology, respiratory, dermatology, urology, pain/analgesia, women’s health, gastroenterology, musculoskeletal, and psychiatry.

Ms. Houghton’s work has led to articles in publications such as British Journal of Dermatology, World Allergy Organization Journal, Infectious Diseases and Therapy, Value in Health, Quality of Life Research, and Contemporary Clinical Trials, alongside presentations at conferences such as the American Thoracic Society, the American Society of Clinical Oncology, the European Academy of Allergy and Clinical Immunology, the European Academy of Dermatology and Venereology, the Multidisciplinary Thoracic Cancers Symposium, the International Society for Pharmacoeconomics and Outcomes, and the International Society for Quality of Life Research.

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