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… potential confounding, typically using methods such as propensity scores, when estimating risk measures of association. In addition, we assist …
… more involved methods than usual. To help researchers new to the methodology, our experts are collaborating on the …
… patterns, impact, and adherence Product safety and risk minimization evaluations (e.g., PASS, REMS) Drug … and retention Statistical analysis plans Reports and publications Data Collection and Management Depending upon …
… can help you prioritize your options. You can calculate a score to rank your options by methodically assigning weights … We can help you assess the relevance of a current or new product’s attributes across its lifecycle—including … information that can help you understand and communicate risk tolerance from patients and other stakeholders to inform …
… needed, we employ advanced statistical techniques such as propensity scoring to control for selection bias, … with a wide range of data partners, including: Behavioral Risk Factor Surveillance System (BRFSS) CPRD Drug Abuse …
… Benefit-Risk Assessment Do your product’s benefits outweigh its … help you navigate the ever-evolving landscape of benefit-risk assessment and meet the requirements of regulatory and … help you identify gaps to inform a strategy for possible new studies to include in your clinical development program …
… activities. To understand disease distribution, risk factors, treatment patterns and impact, comorbidities, … other related factors, and the effectiveness of risk minimization interventions, or to evaluate safety and … observational research ; a literature review ; or a risk management plan, we can provide you with high-quality, …
… the Q-TWiST method to quantitatively assess the benefit/risk tradeoff of your new treatment regimen. Healthcare Resource Utilization Our … to demonstrate the cost and healthcare benefits of your new treatment. Exploratory Data Analysis In addition to …
… osteoporosis in post-menopausal women at high risk for fracture. Because research had shown that the drug … patients) was linked to cancer registry data to identify new osteosarcoma cases. RTI-HS managed the recruitment and … studies showed that a similar risk exists between FORTEO® users and their comparators, or the general population. The …
… outcome regression, inverse probability weighting, and propensity scores) and 1 non-structural approach (high-dimensional propensity scores). The 4 methods yielded the same result: a 30% reduction in the relative risk of death due to a single screening colonoscopy, which is …