Hicks KA, Ghaswalla P, Carrico J, Anderson S, Novy P, Hogea C, Hayney MS. Estimating the cost of university-based outbreaks of serogroup B meningococcal disease with different pre-matriculation vaccination policies in the United States. J Am Coll Health. 2023 Jan 26. doi: 10.1080/07448481.2022.2163854

OBJECTIVE: We developed an Excel-based cost calculator to assess the economic burden of university-based Neisseria meningitidis serogroup B (MenB) outbreaks. Participants: Hypothetical university with 6,354 students.

METHODS: Total societal costs of outbreak were estimated for three MenB pre-matriculation immunization policies—vaccination required, vaccination recommended, and no vaccine policy—under three different cost assumptions (low/mid-range/high cost).

RESULTS: Mid-range cost estimates of an outbreak under “no policy” were $2.60 and $2.70 million (of which 35% were incurred by the university) if targeting all undergraduates for mass vaccination with a two-/three-dose vaccine, respectively. The “required” and “recommended” policies lowered the burden to $2.17–$2.18 million and $2.34–$2.39 million, respectively. For a larger university with 40,000 students, costs were almost $9 million for a two-dose vaccine with “no policy” in place.

CONCLUSION: The economic burden of a university MenB outbreak is substantial, but could be mitigated by a pre-matriculation MenB vaccination requirement or recommendation.

Share on: