Barnett C, Denton BT. Developing near-optimal biomarker-based prostate cancer screening strategies. Presented at the 2016 INFORMS Annual Meeting; November 14, 2016. Nashville, TN.

Recent advances in the development of new biomarker tests, which physicians use for the early detection of cancer, have the potential to improve patient survival by catching cancer at an early stage. We describe a partially observable Markov decision process (POMDP) to compute near-optimal prostate cancer screening strategies. We present results based on Monte Carlo simulation to compare the policies developed using our approximated POMDP methods with those recommended in the medical literature.

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