Literature Reviews

Evidence That Drives Decisions

Digital healthcare technology concept showing a connected globe with medical icons, data analytics, and a person using a stylus on a tabletIn today’s competitive and highly regulated life sciences landscape, making informed decisions requires a deep understanding of the available evidence. At RTI Health Solutions, our literature review services are designed to deliver clarity, confidence, and scientific rigor—whether you're preparing for market access, health technology assessment (HTA), or internal strategic planning.

High-quality literature reviews can help you:

  • Establish definitions, etiology, and diagnosis of a disease
  • Understand epidemiologic, humanistic, and economic burden of a disease
  • Determine treatment guidelines and patterns in clinical practice
  • Identify clinical and cost effectiveness of comparator treatments
  • Formulate best practices in economic modeling methods in a disease area
  • Develop economic model inputs including resource use, cost, and utility estimates
  • Identify health disparities among marginalized populations

How We Can Help You

Our experts can help you with a full spectrum of literature review methodologies tailored to meet your specific goals:

  • Systematic Literature Reviews (SLRs) - Ideal for answering clearly defined research questions with reproducible, high-quality evidence. SLRs are often essential for HTA submissions and meta-analyses.
  • Targeted Literature Reviews - Focused and flexible, these reviews help you gather the latest insights on disease management, treatment patterns, and unmet needs—perfect for internal decision-making or early-stage strategy development.
  • Umbrella Reviews - Aggregate findings from multiple systematic reviews to provide a high-level overview of evolving evidence in a therapeutic area.

Why Choose RTI Health Solutions?

Because literature reviews often serve as the foundation for follow-on research, it is imperative that they are done well and with scientific rigor. At RTI-HS every review is overseen by senior researchers and follows a quality-controlled process—from protocol development to data extraction and synthesis.

Our experts are trained in state-of-the art techniques and can combine the information from a literature review with meta-analyses to synthesize the evidence quantitatively, generating new information that was not available from the individual studies. These results may be used as supplemental evidence, for input to economic models, or in some cases, to support HTA submissions.

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