MSc, Social Research Methods and Statistics
University of Manchester, Greater Manchester, UK
BSc, Psychology: Physical and Mental Health
University of Reading, Berkshire, UK
Katherine Houghton, MSc, is a Director within the Health Economics Database group at RTI-HS. Ms. Houghton has extensive experience in health outcomes research and data analytics including experience in manipulating, cleaning, and conducting analyses of clinical trial and observational data using both Stata and Mplus. Ms. Houghton’s primary responsibilities are designing and implementing observational studies (such as medical record reviews and surveys) and retrospective data analysis. Specifically, Ms. Houghton has expertise in conducting advanced statistical analyses including structural equation modeling and analysis of heterogeneity and identifying, evaluating, and modeling the impact of missing data on study design, analyses, and results. Ms. Houghton’s key area of expertise is the explicit consideration of missing data (including analytic techniques for missing data mechanisms that are nonignorable) and implications on results. She has experience in applying structural equation modeling techniques (including latent growth modeling and growth mixture modeling) under different assumptions around missing data such as multiple imputation, full information maximum likelihood, and pattern-mixture modeling. She also uses latent growth modeling and growth mixture modeling to examine the heterogeneity of responses in clinical trials and observational studies. Ms. Houghton has experience in conducting targeted searches of health care literature and in conducting interviews with patients and clinicians. Ms. Houghton’s therapeutic areas of interest include invasive fungal infections, neurology, oncology, respiratory, dermatology, urology, pain/analgesia, women’s health, gastroenterology, musculoskeletal, and psychiatry.
Ms. Houghton’s work has led to articles in publications such as Value in Health, Quality of Life Research, and Contemporary Clinical Trials, alongside presentations at conferences such as the American Thoracic Society (ATS), the American Society of Clinical Oncology (ASCO), the European Academy of Allergy and Clinical Immunology (EAACI), the European Academy of Dermatology and Venereology (EADV), the Multidisciplinary Thoracic Cancers Symposium, the International Society for Pharmacoeconomics and Outcomes (ISPOR), and the International Society for Quality of Life Research (ISOQOL).