Chris Knight, MSc

Executive Director, Health Economics

Practice Area
Office Location
Manchester, United Kingdom

MSc, Operations Research
University of Birmingham, Birmingham, United Kingdom

BS, Mathematics, Statistics & Computing (2:1)
De Montfort University, Leicester, United Kingdom

Christopher Knight, MSc, is an Executive Director of Health Economics at RTI-HS. He has more than 18 years of experience in operational research. His work has involved the management of projects using health economics, Markov modeling, simulation modeling, and statistical modeling techniques to explore disease progression and the impact of treatment across a range of areas, including hemophilia, psoriatic rheumatoid arthritis, lymphoma, depression, schizophrenia, obesity, and infectious diseases. He has a particular interest in orphan diseases and has developed economic models in osteosarcoma, mucopolysaccharidosis, and Castleman's disease. He has presented his work at professional conferences and has a number of health economic publications in peer-reviewed journals. Mr. Knight has developed innovative mathematical models, including Markov state transition models and Monte-Carlo simulation models both at cohort and individual patient level. He has extensive experience in Microsoft Excel and Visual Basic for Applications programming language. He was previously responsible for leading a team producing rapid review health technology appraisal report for the National Institute for Health and Care Excellence (NICE) in the UK and for applying cost-effective modeling to pharmaceutical companies and service planning for the NHS. Prior to joining RTI-HS, Mr. Knight held operational research analyst positions at the School of Health and Related Research (ScHARR) at the University of Sheffield and the Trent Regional Health Authority.

Mr. Knight is a member of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR). He has published in peer-reviewed journals and has presented his research at numerous international symposia. He is also on the editorial board of the Journal of Comparative Effectiveness Research and serves as a peer reviewer for European Journal of Health Economics, Medical Decision Making, Pharmacoeconomics, Clinical Therapeutics, Current Medical Research and Opinion, Journal of Medical Economics, Applied Health Economics and Health Policy, and Haemophilia.

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