Yen L, Davis KL, Hodgkins P, Loftus EVJr, Erder MH. Direct medical costs of diverticulitis in a US managed care population. Am J Manag Care. 2012;4(5):e118-29.

Objectives: To estimate the economic burden of diverticulitis in a large, real-world managed care population. Study Design: Retrospective cohort analysis.

Methods: Insurance claims from 40 managed care plans covering 50 million lives were analyzed to identify diverticulitis patients aged =18 years with plan enrollment for 6 months before and =12 months after index diagnosis. We estimated resource utilization and both disease-related costs and all-cause costs (in 2009 US dollars) in patients with and without diverticulitis, matched 2:1 on age, sex, and plan enrollment. Cost data were adjusted for patient characteristics, preindex healthcare costs, and comorbidities.

Results: In total, 36,624 diverticulitis patients and 73,248 matched controls were identified. In two-thirds of cases, the index diverticulitis diagnosis occurred in an outpatient setting, 22% occurred in the emergency department (ED), and 12% in hospital. Postindex hospitalization for any reason occurred in 41% of cases (vs 7% of controls; P ‹ .001), regardless of diagnosis setting. Diverticulitis-related hospitalization occurred in 32% of cases. ED visits occurred in 53% of cases (vs 16% of controls; P ‹ .001). Total adjusted disease-related cost per case was $5844, but varied by diagnosis setting ($11,772 for inpatient, $6355 for ED, and $4557 for outpatient). Mean adjusted all-cause hospitalization costs for cases and controls were $8918 and $1138, respectively (P ‹ .001). Total adjusted all-cause costs were $19,627 in cases versus $6309 in controls (P ‹ .001)

Conclusions: Diverticulitis is associated with increased medical resource utilization, resulting in increased costs compared with matched patients without diverticulitis.

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