As a result of these findings, a validated coding algorithm updated to ICD-10 codes to identify psychosis associated with dementia is recommended.
we conducted an antidepressant drug utilization study in five databases in Denmark, Germany, Spain and Sweden.
When using observational data, quantifying the effect of treatment strategies that are sustained over time is not straightforward
ICER's influence on pharmaceutical policy is gaining traction. Here are keys to successful collaboration for evaluations.
A recent population-based observational study highlights important real-world evidence on treatment patterns, health care burden, occurrence of adverse events, and survival outcomes after a metastatic breast cancer (MBC) diagnosis, in particular among older women with the HR+/HER2–subtype in the...
At the Alzheimer’s Association International Conference in July, UsAgainstAlzheimer’s (UsA2) released “Preparing Us for a Cure,” three research products on key areas of Alzheimer’s disease that impact the lives of patients, caregivers, and communities.
Pregnancy-related PASSs are increasingly relying on real-world data to assess potential safety issues that could not be assessed in pre-approval clinical trials.
Atopic dermatitis (AD) and chronic hand eczema (CHE)—both often simply referred to as eczema—are among the most common dermatologic diseases. These conditions cause significant patient burden related to constant, intense itching, visible skin effects, impaired ability to interact with...
At the 16th annual RTI Authors' Awards Dinner held this month, RTI Health Solutions researchers were recognized for their research publishing achievements.
Real-world evidence on adherence, persistence, switching, and dose escalation with biologics in adult IBD in the US is limited.
Josephine Mauskopf has been awarded the Marilyn Dix Smith Leadership Award by ISPOR.
Applied Health Economics for Public Health Practice and Research, has been published. Chapter 9, coauthored by Willings Botha,
Meet researcher Naoko Ronquest, Senior Director in our HE Modeling Program.
Research just published in Value in Health compares FDA and EMA labeling for evidence based on patient-reported outcomes (PROs) of new oncology treatments approved by both agencies.
Regulators and reimbursement authorities want to utilize real-world data more consistently to capture the real-world patient and clinician experience.
This paper describes study methods, challenges, and the study’s progress so far.
Research addressing concerns about the rising cost of health care in the United States
Reliance on statistical significance, and the related statistic, the P-value, is a drawback. Here are alternatives.
The RTI-HS Festive Cheer Score (FCS) is at its peak!
In 2014, a head-to-head clinical trial compared the 96-week efficacy and tolerability of three HIV multi-drug combinations commonly used as initial treatment for individuals with HIV-1 infection.
ISPOR Good Practices for Outcomes Research Provide Guidance for High-, Middle-, and Low-Income Countries
CADASIL, or cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, is a rare genetic disorder caused by mutations in the NOTCH3 gene. It is a neurological degenerative disorder leading to cognitive impairment and eventually vascular dementia.
Multiple myeloma (MM) is an incurable cancer of the bone marrow. It is the third-most-frequent blood cancer in the US, after lymphoma and leukemia. Several new therapies have recently been approved by the United States Food and Drug Administration (FDA) for treatment of MM, including daratumumab...
Patients with drug-resistant epilepsy (DRE) utilize more health care resources and face higher costs than patients who can control their condition with anti-epileptic drugs (AEDs). Despite the long-term proven effectiveness of vagus nerve stimulation (VNS), the treatment is currently...
Qualitative data on patients’ experiences and perspectives typically go uncollected in clinical trial settings. Yet patients’ treatment experiences offer complementary insights and context on topics such as disease management, treatment gaps, and previous treatments outside of those gathered in...