How Does Depression Affect Brain Function and Work Productivity?

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Evidence shows that there is a strong association between major depressive disorder (MDD) and decreased work productivity. RTI Health Solutions researchers, Marci Clark, Dana DiBenedetti, and colleague V. Perez were co-authors on a study published last week that seeks to understand the relationship between MDD-related cognitive dysfunction and work productivity.

Although there is not a lot of research about MDD-related cognitive dysfunction (i.e., decreased memory and reasoning abilities), it may well have a direct negative impact on an employee’s performance. One measure of this is presenteeism – being able to go to work but not really being able to focus on and successfully complete work. The development of new research is especially important because current research supports the idea that the greater the depression, the greater the effect on memory and reasoning skills. These brain deficits can even remain after the depression is in remission.

"There is a clear need to standardize the measurement of cognitive dysfunction and work productivity in future MDD studies, so that we can create reproducible research findings and deepen our understanding of the financial and societal burden caused by MDD," states Dr. Clark.  

Cognitive dysfunction and work productivity in major depressive disorder published June 8th, 2016 in Expert Review of Pharmacoeconomics & Outcomes Research.

 

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