Leadership Team

Allen Mangel, MD, PhD - Executive Vice President, RTI Health Solutions

Allen Mangel, MD, PhD, is a gastroenterologist and Executive Vice President of RTI-HS. Following completion of his medical training, Dr. Mangel did his internship and residency in internal medicine at Duke University Medical Center and then completed his gastroenterology fellowship also at Duke. Following completion of his formal training, he remained on the faculty in the Department of Medicine, Division of Gastroenterology, at Duke for 2 years. Dr. Mangel also has a PhD from the University of Illinois, where his research focused on control of electrical and mechanical activity in gastrointestinal smooth muscle.

After Dr. Mangel left Duke, he joined the gastroenterology clinical research department at GlaxoWellcome, where he conducted numerous clinical trials and directed product development teams. After departing GlaxoWellcome, he became Vice President of Research and Development at Salix Pharmaceuticals. He joined RTI International in 2003 and currently serves as Executive Vice President of RTI-HS.

Dr. Mangel has led or participated in numerous FDA interactions, advisory committee presentations, label negotiations, and new drug application submissions, and he has authored more than 100 publications.

Christopher R. Simmons, CPA - Senior Vice President

Chris Simmons is Senior Vice President of RTI-HS. In this role, he works closely with Allen Mangel and the heads of the research and operations groups to lead the organization. Mr. Simmons joined RTI-HS as its first full-time finance executive in 2003, and over time moved to manage the operations groups of the organization before taking his current role.

Chris is a CPA who has spent more than 30 years in financial and operational positions, with particular focus on early-stage, rapidly growing technology and biotech businesses. Mr. Simmons began his career at KPMG and moved to other public accounting firms whose focus was more on early-stage businesses. Mr. Simmons then moved into corporate finance as controller for Mitsubishi Semiconductor America, Inc., a semiconductor manufacturer. Upon leaving Mitsubishi, Mr. Simmons served 4 years as corporate controller and then vice president of finance for a start-up biotech company, Cogent Neuroscience, Inc.

Just prior to joining RTI-HS, Mr. Simmons consulted for several other early-stage biotech and high-tech businesses as leader of finance.

Senior Scientific Leadership

Senior Operations Leadership