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RTI-HS HomeOur ServicesPharmacoepidemiology and Risk Management - Pharmacoepidemiology › Database Studies

Database Studies

We will work with you to design and implement database studies that address your research questions about epidemiology, health economics, and drug safety. Regardless of the application, our experts use a proven process to deliver dependable results. We have experience with North American and European cross-sectional and longitudinal datasets and have implemented studies to answer research questions on a variety of topics, including:

Economic Outcomes
Disease prevalence, incidence, severity
and impact
Treatment patterns
Comparative effectiveness
Treatment gaps
Drug Safety
Medication adherence and persistence
Incidence of adverse outcomes
Background event rates
Drug exposure in pregnant women and pregnancy outcomes
Health Outcomes
Cost of illness
Cost of treatment
Health care resource utilization
Value of alternative treatments

Access the Best Dataset
We do not have a proprietary position on nor bias toward any specific database, and our status as an independent non-profit research company allows us access to datasets that may not otherwise be available (e.g., Medicare/Medicaid claims data). We can also leverage our relationships with other organizations that have patient health care data (e.g., managed care organizations and government payers) to work collaboratively on your studies. Because of these unique industry positions, you can be confident that the right data are identified and used for your study. Our experience includes, but is not limited to, working with the following data sources:

  • Behavioral Risk Factor Surveillance System (BRFSS)
  • General Practice Research Database (GPRD) (UK)
  • Medstat Commercial Claims and Encounters (CCAE)
  • The Health Improvement Network (THIN) (UK)
  • Health Search Database (Italy)
  • Health Survey of England (HSE)
  • Healthcare Cost and Utilization Project (HCUP) databases
  • Medstat Health and Productivity Management (HPM)
  • Henry Ford Health System
  • i3 Innovus Lab Rx
  • Integrated Health Care Information Systems (IHCIS)
  • Medical Expenditure Panel Survey (MEPS)
  • Medicare and Medicaid claims data
  • National Comorbidity Survey (NCS)
  • National Health and Nutrition Examination Surveys (NHANES)
  • National Health Interview Survey (NHIS)
  • National Hospital Discharge Survey (NHDS)
  • National Medical Expenditure Survey (NMES)
  • National Nursing Home Survey (NNHS)
  • PharMetrics
  • Premier
  • Protocare Sciences
  • Saskatchewan Health (Canada)
  • Scandinavian cancer registries
  • Surveillance, Epidemiology and End Results (SEER) cancer registries
  • SEER-Medicare Linked Database
  • US Renal Data System
  • Veterans Affairs claims data

Methodologies
We determine the most appropriate analytical methods for your database studies, including case control and cohort analysis and pre- to post-index-date comparisons. We will access, process and store data files, extract requisite data depending on the study objective and prepare and implement detailed analysis plans. As appropriate, we also de-identify data, apply sampling statistics for robust inferences, and use other statistical techniques to control for selection bias and other confounders.

Deliverables

  • Detailed reports
  • Technical posters
  • Quality assured data files
  • Presentations at professional meetings
  • Peer-reviewed journal articles

 


 
SENIOR LEADERSHIP

  Elizabeth Andrews, PhD
VP, Pharmacoepidemiology and Risk Management
Susana Perez-Gutthann,
PhD, MD

VP and Global Head, Epidemiology
Kenneth Rothman, DrPH
VP, Epidemiology Research
Patricia Tennis, PhD
Senior Director, Epidemiology

For a full list of scientific staff bios, click here.

 
DOWNLOADS

  Fact Sheets
- Database Analysis
- Pharmacoepidemiology
- Prospective Observational Studies

Other
FDA's Guidance for Industry:
- Good Pharmacovigilance Practices and Pharmacoepidemiologic Assessment
- Establishing Pregnancy Exposure Registries
- Premarketing Risk Assessment
- Development and Use of Risk Minimization Action Plans

EMEA Guidance for Industry:
- Guideline on Risk Management Systems for Medicinal Products for Human Use
- Pharmacovigilance for Medicinal Products for
Human Use
- Template for EU Risk Management Plan


 
CONTACT US

 

To learn more about our research and consulting services, please call us at:

US: +1.800.262.3011
Canada: +1.613.742.8225
Spain: +34.93.241.7766
UK: +44(0)161.232.3400

Or email one of our experts directly.

 

 

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