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RTI-HS HomeOur ServicesHealth Economics › Decision-Analytic Models

Decision-Analytic Models

Economic modeling can help you determine the economic impact of your product when head-to-head clinical trials are not feasible or available. We have broad experience developing economic models that reflect the variables influencing the economic impact of your product and the logic rules to reflect the relationship between them.

How our Clients Use Our Models

Describe disease and treatment pathways
  • Burden of illness estimates
  • Drug and medical resource utilization patterns
  • Surrogate endpoints linked to long-term outcomes
Support strategic planning
  • Compound selection for drug development
  • Clinical trial design (comparators, outcomes)
  • Positioning evaluation (indications, place in treatment pathway)
  • Threshold pricing analysis
  • Product differentiation
Conduct economic evaluations
  • Cost consequences analyses (cost consequences models)
  • Cost effectiveness analyses (cost effectiveness models)
  • Budget impact analyses (budget impact models)
  • Benefit-risk analyses (benefit-risk models)
Inform payer decisions
  • Health technology assessment (HTA) submission models
  • Pricing, reimbursement, and market access (e.g., formulary placement)
  • Field tools (e.g., cost calculators, interactive models)

Types of Economic Models

We advise our clients on the best type of model given their objectives. Our staff are trained in state-of–the-art modeling methods and have experience with:
Decision Tree Models

Markov Health State Models

Simulation Models / Discrete Event Simulation Models

Mathematical Programming

Interactive Models

Our Process for Model Development

We follow a detailed process to build precise, reliable models that account for all relevant variables. Steps include:
  • Review clinical trial data
  • Perform a systematic literature review
  • Gather other available evidence from databases, observational studies and subject matter experts
  • Develop a conceptual framework for the model
  • Run validation checks for clinical and structural logic
  • Quality Control
  • Run primary and sensitivity analyses and summarize the results
  • Develop user interfaces and user guides and training materials depending on your needs

Trust Our Experience

We have extensive experience building both simple and complex models. In collaboration with our clients we have frequently presented our models at scientific conferences or published results in peer-reviewed scientific journals. When you collaborate with RTI-HS to develop a model you can be confident in its predictive ability, and application to your product development and commercialization decisions.

 


 
SENIOR LEADERSHIP

 
Stephen M Beard, MSc
Global Head of Health Economics, Europe
Stephanie R Earnshaw, PhD
Vice President, US Health Economics
Josephine A Mauskopf, PhD
Vice President, Health Economics

For a full list of scientific staff bios, click here.

 
DOWNLOADS

  Fact Sheets
- Health Economics
- Database Analysis
- Pricing and Reimbursement
- Product Value Dossiers
- Health Preference Assessment
- Patient-Reported Outcomes

CONTACT US
To learn more about our research and consulting services, please call us at:
US: +1.800.262.3011
Spain: +34.93.241.7766
UK: +44(0)161.232.3400
Or email one of our experts directly.
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