Mauskopf J, Standaert B, Connolly MP, Jit M, Garrison, Jr. LP, Hutubessy R, Revill P, Severens JL. Economic evaluation of vaccination programs. Presented at the 2020 ISPOR Educational Webinar; January 15, 2020.


From the perspectives of various decision makers, a recent ISPOR Task Force has provided guidelines for those using cost-effectiveness analysis, constrained optimization, or fiscal health modeling in the evaluation of vaccination programs. This webinar will first describe why multiple methods are proposed. It will then highlight the key recommendations for each method as presented in the ISPOR report. Due to recent updates within the World Health Organization guidelines on evaluation of vaccination programs, the webinar will also present highlights from their new guidelines. The webinar includes expected future developments in the evaluation of vaccination programs. There will be an opportunity to pose questions at the end of the webinar.

Participants will gain the following insights & understanding:

  • Economic evaluation methods may need to vary with the decision maker’s objective and their operational context.

  • Evaluation methods can be summarized using the following 4 main topics: decision description, modeling approach, data evaluation, and logistics for doing the analysis.

  • Economic recommendations of the ISPOR Task Force and the World Health Organization on cost-effectiveness analysis are equivalent or compatible.

  • Recommendations of the ISPOR Task Force on constrained optimization and fiscal health modeling provide guidelines for alternative approaches to economic evaluation of vaccination programs.

  • Future development in the economic assessment of vaccines will include their impact beyond health care for cases avoided.

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