Publications - RTI Health Solutions

Publications

As active members of their respective research communities, RTI Health Solutions researchers have published widely in peer-reviewed journals.

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Full Publications List (1553 results)

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2013

Davis, K.L., M. Tangirala, J.L. Meyers, and W. Wei. (2013). "Real-World Comparative Outcomes of US Type 2 Diabetes Patients Initiating Analog Basal Insulin Therapy." Current Medical Research and Opinion, Advance Online Publication.

Abstract Objective To evaluate outcomes in insulin-naive patients with type 2 diabetes mellitus (T2DM) who initiated insulin glargine or insulin detemir. Methods Retrospective data were analyzed... Full Abstract »

Husereau, D., M. Drummond, S. Petrou, C. Carswell, D. Moher, D. Greenberg, F. Augustovski, A.H. Briggs, J. Mauskopf, and E. Loder. (2013). "Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement." European Journal of Health Economics, 14(3):367-372.

Economic evaluations of health interventions pose a particular challenge for reporting. There is also a need to consolidate and update existing guidelines and promote their use in a user friendly... Full Abstract »

Hitsman, B., L. Hogarth, L. Tseng, J.C. Teige, W.G. Shadel, D.B. DiBenedetti, S. Danto, T.C. Lee, L.H. Price, and R. Niaura. (2013). "Dissociable effect of acute varenicline on tonic versus cue-provoked craving in non-treatment-motivated heavy smokers." Drug and Alcohol Dependence, 130(1-3):135-141.

Rationale The effectiveness of varenicline for smoking cessation has been established, but little is known about the psychological processes that mediate this clinical outcome. Objectives This... Full Abstract »

Roskell, N.S., M. Samuel, H. Noack, and B.U. Monz. (2013). "Major bleeding in patients with atrial fibrillation receiving vitamin K antagonists: A systematic review of randomized and observational studies." Europace, 15(6):787-797.

Aims Clinical trials have shown that anticoagulation with vitamin K antagonists (VKAs), e.g. warfarin, decreases the risk of stroke in patients with atrial fibrillation (AF); however, increased... Full Abstract »

Meyers, J., Y. Yu, J.A. Kaye, and K.L. Davis. (2013). "Medicare fee-for-service enrollees with primary acute myeloid leukemia: An analysis of treatment patterns, survival, and healthcare resource utilization and costs." Applied Health Economics and Health Policy, 11(3):275-286.

Background Acute myeloid leukemia (AML) is the most common form of acute leukemia affecting adults, with incidence increasing with patient age. Previous studies have found that older AML patients,... Full Abstract »

Varas-Lorenzo, C., N. Riera-Guardia, B. Calingaert, J. Castellsague, F. Salvo, F. Nicotra, M. Sturkenboom, and S. Perez-Gutthann. (2013). "Myocardial infarction and individual nonsteroidal anti-inflammatory drugs meta-analysis of observational studies." Pharmacoepidemiology and Drug Safety, 22(6):559-570.

Objective To conduct a systematic review of observational studies on the risk of acute myocardial infarction (AMI) with use of individual nonsteroidal anti-inflammatory drugs (NSAIDs). Methods A... Full Abstract »

Nelson, L.M., A. Forsythe, L. McLeod, S. Pulgar, M. Maldonado, T. Coles, Y. Zhang, S.M. Webb, and X. Badia. (2013). "Psychometric evaluation of the Cushing’s Quality-of-Life Questionnaire." Patient: Patient-Centered Outcomes Research, 6(2):113-124.

Background Cushing’s disease (CD) is a rare disorder of chronic hypercortisolism due to an adrenocorticotropic hormone (ACTH)-secreting pituitary corticotroph adenoma. Because hypercortisolism... Full Abstract »

Rothman, K.J., L.A. Wise, H.T. Sorensen, A.H. Riis, E.M. Mikkelsen, and E.E. Hatch. (2013). "Volitional determinants and age-related decline in fecundability: a general population prospective cohort study in Denmark." Fertility and Sterility, 99(7):1958-1964.

OBJECTIVE: To quantify the natural decline in fecundability by age and assess the effect of selected volitional factors. DESIGN: Prospective cohort study of women attempting conception. SETTING: Not... Full Abstract »

Beard, S.M., B.G. von Scheele, G. Nuki, and I.V. Pearson. (2013). "Cost-effectiveness of febuxostat in chronic gout." European Journal of Health Economics, Advance Online Publication.

Our objective was to evaluate data on the cost-effectiveness of febuxostat compared with standard clinical practice with allopurinol in patients with gout that was presented to the Scottish... Full Abstract »

Karve, S., G. Meier, K.L. Davis, D.A. Misurski, and C.C. Wang. (2013). "Influenza-related health care utilization and productivity losses during seasons with and without a match between the seasonal and vaccine virus B lineage." Vaccine, Advance Online Publication.

OBJECTIVE: To assess and compare direct medical costs (incurred by payers) and indirect productivity losses (incurred by employers) associated with influenza seasons with matched or mismatched... Full Abstract »

Burris, H.A., F. Lebrun, H.S. Rugo, T. Beck, M. Piccart, P. Neven, J. Baselga, K. Petrakova, G.N. Hortobagyi, A. Komorowski, E. Chouinard, R. Young, M. Gnant, K.I. Pritchard, L. Bennett, J.-.F. Ricci, H. Bauly, T. Taran, T. Sahmoud, and S. Noguchi. (2013). "Health-related quality of life of patients with advanced breast cancer treated with everolimus plus exemestane versus placebo plus exemestane in the phase 3, randomized, controlled, BOLERO-2 trial." Cancer, 119(10):1908-1915.

BACKGROUND: The randomized, controlled BOLERO-2 (Breast Cancer Trials of Oral Everolimus) trial demonstrated significantly improved progression-free survival with the use of everolimus plus... Full Abstract »

Economic evaluations of health interventions pose a particular challenge for reporting. There is also a need to consolidate and update existing guidelines and promote their use in a user friendly... Full Abstract »

Husereau, D., M. Drummond, S. Petrou, C. Carswell, D. Moher, D. Greenberg, F. Augustovski, A.H. Briggs, J. Mauskopf, E. Loder, and CHEERS Task Force. (2013). "Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement." BJOG, 120(6):765-770.

Economic evaluations of health interventions pose a particular challenge for reporting. There is also a need to consolidate and update existing guidelines and promote their use in a user friendly... Full Abstract »

Pignone, M., S. Earnshaw, C. McDade, and M.J. Pletcher. (2013). "Effect of including cancer mortality on the cost-effectiveness of aspirin for primary prevention in men." Journal of General Internal Medicine, Advance online publication.

BACKGROUND Recent data suggest that aspirin may be effective for reducing cancer mortality. OBJECTIVE To examine whether including a cancer mortality-reducing effect influences which men would... Full Abstract »

Brunelli, S.M., J.J. Gagne, K.F. Huybrechts, S.V. Wang, A.R. Patrick, K.J. Rothman, and J.D. Seeger. (2013). "Estimation using all available covariate information versus a fixed look-back window for dichotomous covariates." Pharmacoepidemiology and Drug Safety, 22(5):542-550.

Purpose When using claims data, dichotomous covariates (C) are often assumed to be absent unless a claim for the condition is observed. When available historical data differs among subjects,... Full Abstract »

Gnanasakthy, A., C. DeMuro, and C. Boulton. (2013). "Integration of patient-reported outcomes in multiregional confirmatory clinical trials." Contemporary Clinical Trials, 35(1):62-69.

Introduction The increasing complexities of conducting multiregional trials and an evolving regulatory environment contribute to unprecedented new challenges for use of patient-reported outcome... Full Abstract »

Mikkelsen, E.M., A.H. Riis, L.A. Wise, E.E. Hatch, K.J. Rothman, and H. Toft Sorensen. (2013). "Pre-gravid oral contraceptive use and time to pregnancy: a Danish prospective cohort study." Human Reproduction, 28(5):1398-1405.

STUDY QUESTION Is there an association between oral contraceptive (OC) use (age at the start of use, duration of use, ethinylestradiol dose and generation) and time to pregnancy (TTP)? SUMMARY... Full Abstract »

Hauber, A.B., A.O. Fairchild, and F.R. Johnson. (2013). "Quantifying benefit–risk preferences for medical interventions: An overview of a growing empirical literature." Applied Health Economics and Health Policy, Advance online publication.

Decisions regarding the development, regulation, sale, and utilization of pharmaceutical and medical interventions require an evaluation of the balance between benefits and risks. Such evaluations... Full Abstract »

von Scheele, B., M. Fernandez, S.L. Hogue, and W.J. Kwong. (2013). "Review of economics and cost-effectiveness analyses of anticoagulant therapy for stroke prevention in atrial fibrillation in the US." Annals of Pharmacotherapy, 47(5):671-685.

OBJECTIVE: To summarize the available evidence on the issues in health economics related to oral anticoagulation for stroke prevention in atrial fibrillation (AF) in the US. DATA SOURCES: A... Full Abstract »

Lubbeke, A., G. Garavaglia, K.J. Rothman, A. Bonvin, C. Roussos, H. Miozzari, and P. Hoffmeyer. (2013). "Statins may reduce femoral osteolysis in patients with total hip arthroplasty." Journal of Orthopaedic Research, 31(5):814-820.

In experimental studies, statin use has been associated with reduction of osteoclastic activity and promotion of bone formation around implants. Moreover, a large clinical study recently reported a... Full Abstract »

Displaying 1 through 20 of 1553 items.

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