Publications - RTI Health Solutions

Publications

As active members of their respective research communities, RTI Health Solutions researchers have published widely in peer-reviewed journals.

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Full Publications List (1341 results)

Displaying 1 through 20 of 1341 items.

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2012

Poulos, C., A. Riewpaiboon, J.F. Stewart, J. Clemens, S. Guh, M. Agtini, D. Sur, Z. Islam, M. Lucas, and D. Whittington. (2012). "Costs of illness due to endemic cholera." Epidemiology and Infection, 140(03):500-509.

SUMMARYEconomic analyses of cholera immunization programmes require estimates of the costs of cholera. The Diseases of the Most Impoverished programme measured the public, provider, and patient... Full Abstract »

Huybrechts, K.F., K.J. Rothman, M.A. Brookhart, R.A. Silliman, S. Crystal, T. Gerhard, and S. Schneeweiss. (2012). "Variation in antipsychotic treatment choice across US nursing homes." Journal of Clinical Psychopharmacology, 32(1):11-17.

Objective: Despite serious safety concerns, antipsychotic medications continue to be used widely in US nursing homes. The objective of this study was to quantify the variation in antipsychotic... Full Abstract »

Lavonas, E.J., J.F. Fries, D.E. Furst, K.J. Rothman, A. Stergachis, A.J. Vaida, D. Zelterman, K.M. Reynolds, J.L. Green, and R.C. Dart. (2012). "Comparative risks of non-prescription analgesics: A structured topic review and research priorities." Expert Opinion on Drug Safety, 11(1):33-44.

Objective: The aims of this report are to quantify and compare competing risks associated with the use of non-prescription analgesics (daily doses of acetaminophen ? 4000 mg, aspirin ? 4000 mg,... Full Abstract »

Strutton, D.R., R.A. Farkouh, S.R. Earnshaw, S. Hwang, U. Theidel, S. Kontodimas, R. Klok, and S. Papanicolaou. (2012). "Cost-effectiveness of 13-valent pneumococcal conjugate vaccine: Germany, Greece, and The Netherlands." Journal of Infection , 64(1):54-67.

Background - Seven-valent pneumococcal conjugate vaccine (PCV7) had profound public-health impacts and is considered cost-effective and potentially cost saving. Two new PCVs have been launched, a... Full Abstract »

Mauskopf, J., A. Brogan, S.E. Talbird, and S. Martin. (2012). "Cost-effectiveness of combination therapy with etravirine in treatment-experienced adults with HIV-1 infection." AIDS, 26(3):355-364.

Objective: To assess the cost-effectiveness of etravirine (INTELENCE), a novel nonnucleoside reverse transcriptase inhibitor, used in combination with a background regimen that included... Full Abstract »

Mauskopf, J.A., J.B. Graham, J.P. Bae, K. Ramaswamy, A.J. Zagar, E.A. Magnuson, D.J. Cohen, and E.S. Meadows. (2012). "Cost-effectiveness of prasugrel in a US managed care population." Journal of Medical Economics, 15(1):166-174.

Objective: Decision-makers in the US may be interested in the applicability to their populations of cost-effectiveness results generated from clinical trial populations. Methods: An economic model... Full Abstract »

Qi, J., Y. Yang, H. Zhu, J. Wang, Y. Jia, N. Liu, Y. Song, L. Zan, X. Zhang, M. Zhou, Y. Gu, D.G. Hicks, and P. Tang. (2012). "Expression of the androgen receptor and its correlation with molecular subtypes in 980 Chinese breast cancer patients." Breast Cancer: Basic and Clinical Research, 6:1-8.

Background: Recent studies have shown that androgen displays an inhibitory effect on breast cancer cell lines that express androgen receptor (AR) but not estrogen receptor (ER) and progesterone... Full Abstract »

Toback, S.L., R. Beigi, P. Tennis, F. Sifakis, B. Calingaert, and C.S. Ambrose. (2012). "Maternal outcomes among pregnant women receiving live attenuated influenza vaccine." Influenza and Other Respiratory Viruses, 6(1):44-51.

Background? Although the live attenuated influenza vaccine (LAIV) prescribing information contains warnings/precautions against use during pregnancy, administration of LAIV to pregnant women does... Full Abstract »

Graham, C.N., J.A. Mauskopf, A.H. Lawson, H. Ascher-Svanum, and D. Bruhn. (2012). "Updating and confirming an industry-sponsored pharmacoeconomic model: Comparing two antipsychotics in the treatment of schizophrenia." Value in Health, 15(1):55-64.

Objective This study updated a 2001 decision economic model that used indirect data and confirmed its findings by developing a new cost-effectiveness model by using now available head-to-head data.... Full Abstract »

2011

Rassen, J.A., R.J. Glynn, K.J. Rothman, S. Setoguchi, and S. Schneeweiss. (2011). "Applying propensity scores estimated in a full cohort to adjust for confounding in subgroup analyses." Pharmacoepidemiology and Drug Safety, Early View.

Background A correctly specified propensity score (PS) estimated in a cohort (“cohort PS”) should, in expectation, remain valid in a subgroup population. Objective We sought to determine whether... Full Abstract »

Herring, W.L., and J.W. Herrmann. (2011). "A stochastic dynamic program for the single-day surgery scheduling problem." IIE Transactions on Healthcare Systems Engineering , 1(4):213-225.

Scheduling elective surgeries involves sequential decision-making on the part of the operating room (OR) manager, who must continually balance the costs of deferring waiting cases and blocking... Full Abstract »

Myers, J.A., J.A. Rassen, J.J. Gagne, K.F. Huybrechts, S. Schneeweiss, K.J. Rothman, M.M. Joffe, and R.J. Glynn. (2011). "Effects of adjusting for instrumental variables on bias and precision of effect estimates." American Journal of Epidemiology, 174(11):1213-1222.

Recent theoretical studies have shown that conditioning on an instrumental variable (IV), a variable that is associated with exposure but not associated with outcome except through exposure, can... Full Abstract »

Wu, Y., M.M. Amonkar, B.H. Sherrill, J. O'Shaughnessy, C. Ellis, J. Baselga, K.L. Blackwell, and H.J. Burstein. (2011). "Impact of lapatinib plus trastuzumab versus single-agent lapatinib on quality of life of patients with trastuzumab-refractory HER2+ metastatic breast cancer." Annals of Oncology, 22(12):2582-2590.

BACKGROUND: Progression-free survival (PFS) was significantly longer for the lapatinib plus trastuzumab (L+T) arm than for L alone in a phase III, randomized, open-label study of women with human... Full Abstract »

Sherrill, B., B. Sherif, M.M. Amonkar, J. Maltzman, L. O'Rourke, and S. Johnston. (2011). "Quality-adjusted survival analysis of first-line treatment of hormone-receptor-positive HER2+ metastatic breast cancer with letrozole alone or in combination with lapatinib." Current Medical Research and Opinion, 27(12):2245-2252.

Abstract Aim: Compare first-line lapatinib plus letrozole (L + Let) versus letrozole monotherapy (Let) in hormone-receptor-positive HER2 + metastatic breast cancer, employing Q-TWiST... Full Abstract »

Williams, L.K., E.L. Peterson, K. Wells, B.K. Ahmedani, R. Kumar, E.G. Burchard, V.K. Chowdhry, D. Favro, D.E. Lanfear, and M. Pladevall. (2011). "Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence." Journal of Allergy and Clinical Immunology, 128(6):1185-1191.

Background - Asthma is an inflammatory condition often punctuated by episodic symptomatic worsening, and accordingly, patients with asthma might have waxing and waning adherence to controller therapy.... Full Abstract »

Sherrill, B., M. Halpern, S. Khan, J. Zhang, and S. Panjabi. (2011). "Single-pill vs free-equivalent combination therapies for hypertension: A meta-analysis of health care costs and adherence." Journal of Clinical Hypertension, 13(12):898-909.

This meta-analysis compares health care resource use costs, adherence, and persistence between groups of patients taking antihypertensives as single-pill combinations (SPCs) vs free-equivalent... Full Abstract »

Varas-Lorenzo, C., N. Riera-Guardia, B. Calingaert, J. Castellsague, A. Pariente, L. Scotti, M. Sturkenboom, and S. Perez-Gutthann. (2011). "Stroke risk and NSAIDs: a systematic review of observational studies." Pharmacoepidemiology and Drug Safety, 20(12):1225-1236.

AIMS: To perform a quantitative systematic review of observational studies on the risk of stroke associated with the use of individual NSAIDs. METHODS AND RESULTS: Searches were conducted using the... Full Abstract »

Ahern, T.P., L. Pedersen, C. Svaerke, K.J. Rothman, H.T. Sorensen, and T.L. Lash. (2011). "The association between vitamin K antagonist therapy and site-specific cancer incidence estimated by using heart valve replacement as an instrumental variable." American Journal of Epidemiology, 174(12):1382-1390.

Earlier studies suggest a protective association between vitamin K antagonist (VKA) anticoagulants and the incidence of cancer. The authors examined the associations between VKA therapy and... Full Abstract »

Chirila, C., D. Odom, G. Devercelli, S. Khan, B.N. Sherif, J.A. Kaye, I. Molnar, and B. Sherrill. (2011). "Meta-analysis of the association between progression-free survival and overall survival in metastatic colorectal cancer." Int J Colorectal Dis , Online First.

PURPOSE: The validity of progression-free survival (PFS) as a surrogate endpoint for overall survival (OS) in metastatic colorectal cancer (mCRC) trials has been studied, primarily in first-line... Full Abstract »

Police, R.L., T. Foster, and K.S. Wong. (2011). "Adoption and use of health information technology in physician practice organisations: Systematic review." Informatics in Primary Care, 18(4):245-258.

Background: Health information technology (HIT) has the potential to improve clinical outcomes, increase health provider productivity and reduce healthcare costs. Over half of all patient care is... Full Abstract »

Displaying 1 through 20 of 1341 items.

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